Publications 2000-2012 (TP53 database only)

Edlund K, Larsson O, Ameur A, Bunikis I, Gyllensten U, Leroy B, Sundstrom M, Micke P, Botling J, Soussi T (2012) Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors. Proc Natl Acad Sci U S A 109: 9551-9556.
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Soussi T (2011) TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade. Adv Cancer Res 110: 107-139.
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Soussi T (2011) Advances in carcinogenesis: A historical perspective from observational studies to tumor genome sequencing and TP53 mutation spectrum analysis. Biochim Biophys Acta 1816: 199-208.
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Soussi T, Hamroun D, Hjortsberg L, Rubio-Nevado JM, Fournier JL, Beroud C (2010) MUT-TP53 2.0: a novel versatile matrix for statistical analysis of TP53 mutations in human cancer. Hum Mutat 31: 1020-1025.
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Zenz T, Vollmer D, Trbusek M, Smardova J, Benner A, Soussi T, Helfrich H, Heuberger M, Hoth P, Fuge M, Denzel T, Habe S, Malcikova J, Kuglik P, Truong S, Patten N, Wu L, Oscier D, Ibbotson R, Gardiner A, Tracy I, Lin K, Pettitt A, Pospisilova S, Mayer J, Hallek M, Dohner H, Stilgenbauer S (2010) TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations. Leukemia 24: 2072-2079.
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Carlsson J, Soussi T, Persson B (2009) Investigation and prediction of the severity of p53 mutants using parameters from structural calculations. FEBS J 276: 4142-4155.
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Berglind H, Pawitan Y, Kato S, Ishioka C, Soussi T (2008) Analysis of p53 mutation status in human cancer cell lines: a paradigm for cell line cross-contamination. Cancer Biol Ther 7: 699-708.
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Soussi Zander C, Soussi T (2008) Breast-cancer stromal cells with TP53 mutations. N Engl J Med 358: 1635; author reply 1636. 18411430
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Soussi T, Ishioka C, Claustres M, Beroud C (2006) Locus-specific mutation databases: pitfalls and good practice based on the p53 experience. Nat Rev Cancer 6: 83-90.
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Hamroun D, Kato S, Ishioka C, Claustres M, Beroud C, Soussi T (2006) The UMD TP53 database and website: update and revisions. Hum Mutat 27: 14-20.
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Iacopetta B, Russo A, Bazan V, Dardanoni G, Gebbia N, Soussi T, Kerr D, Elsaleh H, Soong R, Kandioler D, Janschek E, Kappel S, Lung M, Leung CS, Ko JM, Yuen S, Ho J, Leung SY, Crapez E, Duffour J, Ychou M, Leahy DT, O’Donoghue DP, Agnese V, Cascio S, Di Fede G, Chieco-Bianchi L, Bertorelle R, Belluco C, Giaretti W, Castagnola P, Ricevuto E, Ficorella C, Bosari S, Arizzi CD, Miyaki M, Onda M, Kampman E, Diergaarde B, Royds J, Lothe RA, Diep CB, Meling GI, Ostrowski J, Trzeciak L, Guzinska-Ustymowicz K, Zalewski B, Capella GM, Moreno V, Peinado MA, Lonnroth C, Lundholm K, Sun XF, Jansson A, Bouzourene H, Hsieh LL, Tang R, Smith DR, Allen-Mersh TG, Khan ZA, Shorthouse AJ, Silverman ML, Kato S, Ishioka C (2006) Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study. Ann Oncol 17: 842-847.
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Soussi T, Rubio-Nevado JM, Ishioka C (2006) MUT-TP53: a versatile matrix for TP53 mutation verification and publication. Hum Mutat 27: 1151-1154.
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Soussi T, Asselain B, Hamroun D, Kato S, Ishioka C, Claustres M, Beroud C (2006) Meta-analysis of the p53 mutation database for mutant p53 biological activity reveals a methodologic bias in mutation detection. Clin Cancer Res 12: 62-69.
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Soussi T, Kato S, Levy PP, Ishioka C (2005) Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations. Hum Mutat 25: 6-17.
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Beroud C, Hamroun D, Collod-Beroud G, Boileau C, Soussi T, Claustres M (2005) UMD (Universal Mutation Database): 2005 update. Hum Mutat 26: 184-191.
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Russo A, Bazan V, Iacopetta B, Kerr D, Soussi T, Gebbia N (2005) The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment. J Clin Oncol 23: 7518-7528.
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Soussi T, Beroud C (2003) Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides. Hum Mutat 21: 192-200.
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Holmila R, Fouquet C, Cadranel J, Zalcman G, Soussi T (2003) Splice mutations in the p53 gene: case report and review of the literature. Hum Mutat 21: 101-102.
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Beroud C, Soussi T (2003) The UMD-p53 database: new mutations and analysis tools. Hum Mutat 21: 176-181.
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Soussi T, Beroud C (2001) Assessing TP53 status in human tumours to evaluate clinical outcome. Nat Rev Cancer 1: 233-240. 11902578

Beroud C, Collod-Beroud G, Boileau C, Soussi T, Junien C (2000) UMD (Universal mutation database): a generic software to build and analyze locus-specific databases. Hum Mutat 15: 86-94.
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Soussi T, Dehouche K, Beroud C (2000) p53 website and analysis of p53 gene mutations in human cancer: forging a link between epidemiology and carcinogenesis. Hum Mutat 15: 105-113.
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